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Conception
Berkeley, California, USA
Source: Conception careers · View original posting
From Conception's posting. “We” and “our” refer to the employer.
Senior Scientist, Organoid and Tissue Systems
PhD plus postdoctoral training or equivalent industry experience (typically 3+ years post-PhD).
Conception is pioneering the future of reproductive biology by generating functional human eggs from induced pluripotent stem cells (iPSCs).
Our work combines stem cell biology, cell engineering, developmental biology, tissue engineering, and computation to recreate the key stages of human ovarian development in the lab. We recently shared that we have, for the first time, generated early human egg cells and follicles entirely from stem cells
. The next major challenge is to support those fully stem cell-derived follicles through growth and maturation.
We are building a world-class scientific team to solve this problem and create new possibilities for fertility and reproductive health.
The position
We are seeking an exceptionally strong, hands-on senior scientist to help drive the development of advanced 3D tissue and organoid systems.
The strongest candidates will have personally built new differentiation, organoid, or complex multicellular culture systems and worked through the biological and technical challenges required to improve their fidelity, maturation, function, and reproducibility.
Direct reproductive biology experience is not required. We are excited about scientists who have built difficult systems in other tissues and can bring new approaches to ovarian biology.
In this role, you will lead the development of advanced stem-cell-derived ovarian tissue systems central to Conception’s mission. You will work across developmental biology, cell-cell interactions, tissue organization, the cellular microenvironment, matrix and mechanics, signaling, metabolism, computation, and culture design to build systems that more faithfully recapitulate human ovarian biology.
You will build from a strong scientific foundation, including advanced stem-cell-derived ovarian tissue systems, extensive internal datasets, and human reference biology. You will work closely with a strong cross-functional team across stem cell biology, developmental biology, reproductive biology, computation, and engineering.
We will provide the resources and flexibility to test new approaches, bring in the right tools and collaborators, and build additional expertise around the program as it grows. You will have direct support from scientific and company leadership and meaningful ownership over the direction of the work.
We are well funded and well connected in Silicon Valley. We offer competitive pay, company equity, and excellent healthcare benefits for these positions.
To learn more about the original mouse proof of concept to live birth that inspired us, see https://www.nature.com/articles/nature20104
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