Senior Director, IT - G&A

MISSION

Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.

POSITION SUMMARY

Lead the technology strategy, delivery, and operational support for Mirum's General & Administrative functions, including Finance, Accounting, Human Resources, and Legal. This role will serve as the senior IT business partner and single point of accountability for enterprise applications, ensuring that technology investments support scalable operations, effective controls, reliable data, and excellent employee experience.

The ideal candidate brings a strong blend of life sciences business knowledge, enterprise applications expertise, financial and compliance acumen, and people leadership. This leader will own the G&A technology roadmap end-to-end, chair the G&A Functional IT Governance Committee, and lead a team of employees, consultants, vendors, and managed-service partners.

JOB FUNCTIONS/RESPONSIBILITIES

Strategic Leadership & Business Partnership

Serve as the IT thought partner to Finance, Accounting, Human Resources, Legal, and other corporate-function leaders.

Develop and execute a multi-year G&A technology roadmap aligned with business priorities, company growth, risk management, and compliance requirements. This roadmap represents a $3.5–4.0M investment over 24 months across six workstreams, currently in execution

Act as the front door for G&A technology demand, translating business priorities into clear capabilities, investment proposals, and delivery plans.

Chair the G&A Functional IT Governance Committee, facilitating prioritization, approvals, trade-off decisions, and escalation of cross-functional, budget, or compliance matters.

Application Portfolio & Program Delivery

Own the lifecycle, roadmap, integration, enhancement, and support of business-critical G&A platforms, including ERP and financial systems, planning and reporting tools, HR and payroll systems, legal and corporate applications, and related integrations.

Lead complex cross-functional initiatives such as finance process automation, systems integration, master-data improvements, reporting modernization, and budget-versus-actuals reconciliation.

Ensure prioritized projects are delivered on time, within scope, within budget, and with measurable business outcomes using established IT governance and project delivery practices.

Define business requirements, process designs, data definitions, testing strategies, and business acceptance criteria in partnership with functional stakeholders.

Own change management, training, communications, and adoption planning for new and enhanced solutions.

Financial Controls, Compliance & Risk Management

Ensure SOX-relevant systems and processes maintain appropriate application controls, access controls, segregation of duties, change controls, and audit evidence.

Partner with Finance, Internal Audit, Legal, Privacy, Security, and external auditors to assess risks, remediate control gaps, and support audits and compliance reviews.

Ensure G&A applications comply with applicable data privacy, records-management, cybersecurity, and corporate policy requirements.

Maintain clear system ownership, support models, documentation, disaster-recovery expectations, and vendor accountability for critical platforms.

Team Leadership, Budget & Vendor Management

Build, lead, develop, and retain a high-performing G&A IT team of employees and contractors, setting clear goals, priorities, roles, and performance expectations.

Plan the domain's annual resources and budget across personnel, software, services, projects, and vendors; monitor spend and forecast budget versus actuals with FP&A.

Determine the appropriate mix of internal capability, consultants, managed services, and software partners based on business criticality, required knowledge, scalability, and cost.

Manage vendor performance, contracts, renewals, service levels, delivery quality, and issue escalation.

Foster a culture of collaboration, accountability, customer focus, continuous improvement, and practical innovation.

Operations & Continuous Improvement

Ensure reliable day-to-day operation and support of G&A applications, with clear service levels, incident management, root-cause analysis, and problem resolution.

Drive process simplification, workflow automation, data-quality improvements, integration reliability, technical-debt reduction, and platform optimization.

Partner with Data & AI, Infrastructure, Security, and the IT PMO to ensure solutions align with enterprise architecture, data governance, security, and delivery standards.

Establish and track meaningful service, delivery, financial, adoption, risk, and business-value measures for the G&A portfolio.

QUALIFICATIONS

• Education /Experience: Bachelor's degree in Information Technology, Computer Science, Business, Finance, or a related field; master's degree preferred.
• 12+ years of progressive IT experience, including 6+ years in leadership roles supporting Finance, Accounting, Human Resources, Legal, or other G&A functions.
• Experience leading enterprise application portfolios, cross-functional programs, teams, budgets, and vendors in a regulated life sciences or similarly controlled environment.
• Technical & Domain Expertise
• Deep experience with ERP and finance platforms, financial planning and reporting, HRIS and payroll, legal or corporate applications, and enterprise integrations.
• Strong understanding of core Finance and Accounting processes, including procure-to-pay, record-to-report, order-to-cash, budgeting and forecasting, financial close, and management reporting.
• Working knowledge of SOX controls, segregation of duties, audit requirements, data privacy, cybersecurity, and vendor-risk management.
• Experience with business process design, integration architecture, data quality, reporting, workflow automation, and cloud-based enterprise applications.
• Leadership & Interpersonal Skills
• Proven ability to partner with and influence senior business leaders while translating technical complexity into clear business choices and outcomes.
• Demonstrated success building teams, developing talent, managing competing priorities, and creating accountability across employees, contractors, and vendors.
• Strong executive communication, facilitation, negotiation, financial-management, and decision-making skills.
• Pragmatic, hands-on leader who can set strategy while ensuring disciplined execution and reliable operations in a fast-paced, growing company.
• KNOWLEDGE, SKILLS AND ABILITIES
• Ability to create and operate a business-aligned technology roadmap and governance process for multiple corporate functions.
• Ability to balance speed, cost, usability, control, and scalability when making technology and sourcing decisions.
• Strong analytical and problem-solving capability, with attention to data integrity, process controls, and operational detail.
• Commitment to Mirum's values and to building collaborative, trusted relationships across the organization.

The salary range for this position is $280,000 to $300,000 USD. Compensation will be determined based on several factors including, but not limited to; skill set, years of experience, and the employee’s geographic location. Please note that the required compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits unless otherwise provided.

Mirum Pharmaceuticals is committed to Equal Employment Opportunity (EEO) and to compliance with all Federal, State and Local laws that prohibit employment discrimination on the basis of race, age, national origin, ethnicity, religion, gender, gender identity, pregnancy, marital status, sexual orientation, citizenship, genetic disposition or characteristics, disability, veteran’s status or any other classification protected by applicable State/Federal/Local laws.

Mirum Pharmaceuticals provides reasonable accommodation for qualified individuals with disabilities and disabled veterans in job application procedures.