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GT Bio
Cambridge, Massachusetts, United States
Source: GT Bio careers · View original posting
From GT Bio's posting. “We” and “our” refer to the employer.
GT Biosciences is a seed-stage techbio startup building Deliveromics, the first AI-powered, high-throughput, multiplexed in vivo data engine for cracking the design rules of drug delivery. Founded by MIT PhDs and an MIT professor, backed by top-tier investors, we’re creating next-generation, non-viral, cell-type-specific delivery vehicles. We’re a small, fast-moving, science-obsessed team on a mission to make routine in vivo cell reprogramming possible.
We’re a small, fast-moving, science-obsessed team on a mission to make routine in vivo cell reprogramming possible. We value transparency and collaboration, and seek teammates who thrive in an open, cooperative environment and want to grow together with the team and the company.
GT Biosciences is seeking a mission-driven, multidisciplinary Scientist in Organic Chemistry and Bioconjugation to join our Deliveromics Platform Development team. In this role, you will lead the design, synthesis, and characterization of novel ligands, linkers, and conjugates for targeted delivery applications.
You will develop and optimize multi-step synthetic routes and bioconjugation strategies across a broad range of molecular formats, including oligonucleotides, peptides, proteins, lipids, small molecules, and other therapeutic payloads. You will work end-to-end, from molecular design and synthesis through purification, analytical characterization, formulation integration, and evaluation in cellular, mouse, and non-human primate studies.
You will independently plan and execute experiments, troubleshoot complex chemistry challenges, analyze data, and clearly communicate results. As one of the earliest scientific hires at an emerging biotech, you will help shape our chemistry capabilities, collaborate closely with biologists, formulation scientists, and engineers, and contribute directly to the development of transformative delivery technologies. This is a full-time, in-person position based in Cambridge, MA.
What success looks like: You establish a reliable chemistry engine that rapidly turns targeting concepts into purified, fully characterized conjugates ready for formulation and in vivo testing.
Competitive salary, meaningful equity ownership, and flexible, generous health benefits.
The opportunity to build a core chemistry capability and shape an emerging delivery platform from an early stage.
Close collaboration across chemistry, AI, protein engineering, formulation, automation, and in vivo biology.
A small, ambitious team that values rigorous science, candid discussion, and rapid learning.
We don't expect anyone to know everything.
We learn together, support each other, and get better every day!
If you are ready to make an impact, we would love to hear from you.
GT Biosciences is an Equal Opportunity Employer. We celebrate diversity and are committed to fostering an inclusive, supportive environment for all employees. All qualified applicants will be considered without regard to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation.
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