layiq

/la·yiq/adjective

worthy; deserving; fitting; suitable.

A role, opportunity, or path that merits attention, time, and pursuit.

Scientist / Sr. Scientist In Vivo Translational Sciences at Altos Labs | LAYIQ

Lead the full lifecycle of in vivo pharmacology studies across multiple projects — providing in vivo pharmacology and physiology expertise from study design and model selection through dosing and in-life monitoring, tissue collection and processing, data analysis, interpretation, and reporting of results to program teams
Contribute to selection of pharmacodynamic and target-engagement readouts
Contribute to building translational strategy by leveraging in vivo research for target validation and candidate progression
Develop, characterize, and implement new animal models; including models of fibrosis and other age-related pathologies
Evaluate and implement new technologies, platforms, and best practices for in vivo research to enhance study efficiency and quality
Execute studies in both mice and rats, including conducting survival surgeries to establish rodent models using aseptic technique
Occasionally execute downstream ex vivo analyses
Maintain detailed documentation of all studies in the electronic lab notebook to ensure data integrity and traceability
Collaborate with cross-functional partners across discovery biology, pharmacology and assay sciences, DMPK, and technology development to advance therapeutic programs
Ensure all in vivo work meets IACUC-approved protocols and uphold the highest ethical standards in study conduct
Contribute to a team culture that promotes continuous improvement, ownership, professional growth, and inclusion
Who You Are
Ph.D. in biological sciences with a minimum of 3-5 years (Scientist) and 6+ years (Sr. Scientist) of industry experience in a drug discovery and development setting
Extensive expertise with all aspects of in vivo rodent research (various dosing routes, anesthesia, surgical procedures, necropsy, tissue processing, etc.) in both mice and rats
Strong commitment to animal welfare and a 3Rs-centered approach to experimental design
Excellent communication skills for effective collaboration with internal teams and external CRO partners
Exceptional organizational skills, strong attention to detail, and the ability to work independently and collaboratively in a dynamic environment
Demonstrate creative thinking and a proactive, solution-oriented mindset; able to design, troubleshoot, and refine complex in vivo studies with resourcefulness and innovation
High-level problem-solving ability with strong analytical thinking and the capacity to make practical, data-driven decisions
Hands-on experience with molecular and cell biology techniques (RNA/DNA extraction, PCR, Western blot, ELISA, and small molecule/biologic assays)
Willingness and ability to work in a lab/vivarium environment for the majority of working hours, including supporting weekend study needs

Scientist / Sr. Scientist In Vivo Translational Sciences

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