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Washington University in St Louis
Washington University Medical Campus; Jeffrey T. Fort Neuroscience Research Building
Source: Washington University in St Louis careers · View original posting
From Washington University in St Louis's posting. “We” and “our” refer to the employer.
Location
SAINT LOUIS, MO 63110

 Scheduled Hours
40
Position Summary
The Orr Lab is seeking support for computational and quantitative research focused on aging, neurodegeneration, and human disease. The successful candidate will work closely with bioinformatics scientists, experimental researchers, and collaborators to analyze, integrate, and interpret complex high-dimensional molecular datasets.
This position will support projects spanning multiple omics technologies, including spatial proteomics and transcriptomics, bulk transcriptomics, single-cell and single-nucleus RNA sequencing, proteomics, epigenomics, and whole-exome/genomic sequencing. The candidate will contribute to the full analytical workflow, including data quality assessment, preprocessing and normalization, statistical modeling, dimensionality reduction, network analysis, multi-omic integration, visualization, and biological interpretation.
A major focus of the position will be the development and application of statistically rigorous, reproducible, and scalable computational workflows. The ideal candidate will understand not only how to use established bioinformatics tools, but also how to select appropriate analytical approaches based on the experimental design, structure of the data, and biological question.
The individual will work in a highly collaborative research environment and will contribute analytical results to manuscripts, abstracts, presentations, grant applications, and ongoing research discussions.
Job Description
Algorithms and computer software for omics-based data sets [high-throughput, massively parallel genomic/proteomic/clinical.]
Data management and analysis solutions that aid in the storage, investigation, and dissemination of large data sets.
Independent research projects, including design of research protocols and development of procedures for the collection, verification, and management of data.
Develop clear, informative, and publication-quality data visualizations, including heatmaps, dimensionality-reduction plots, statistical summaries, pathway/network visualizations, and other figures appropriate for scientific communication.
Perform data quality control, preprocessing, normalization, filtering, identifying technical artifacts, outliers, batch effects, and other sources of unwanted variation.
Clustering
Evaluates commercial and academic bioinformatics software.
Work closely with wet-lab scientists, neuropathologists, statisticians, computational researchers, and external collaborators to translate biological questions into appropriate computational analyses.
Trains other researchers on the everyday use of analysis software and research databases.
Assists with grant preparation and reporting of methods, data, and results.
Solves practical problems relating to difficulties with equipment or test subjects; suggests technical or procedural improvements in testing methods.
Equipment
Office Equipment
The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.
Required Qualifications
Bachelor's degree
No specific certification/professional license is required for this position.
Research (4 Years)
Not Applicable
A driver's license is not required for this position.
More About This Job
Compensation
$55,200.00 - $100,000.00 / Annually
The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.
Questions
For frequently asked questions about the application process, please refer to our External Applicant FAQ .
Accommodation
If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.
Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
LAYIQ is an independent job-discovery service. This listing does not imply a partnership with or endorsement by the employer. Review the original posting for current details and availability.
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