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University of Chicago
Chicago, IL; Hyde Park Campus
Source: University of Chicago careers · View original posting
From University of Chicago's posting. “We” and “our” refer to the employer.
Department
BSD MED - Genetic Medicine - De Jesus Research Staff
The De Jesus Laboratory studies the role of RNA modifications, particularly N6-methyladenosine (m6A), in pancreatic islet biology and diabetes. This Laboratory combines molecular biology, genomics, bioinformatics, genetic models, and human islet studies to understand mechanisms regulating β-cell function, stress responses, and disease progression in diabetes.
The De Jesus Laboratory develops and applies cutting-edge sequencing technologies, including single-cell epitranscriptomic approaches, to investigate gene regulation in endocrine cells.
Job Summary
The Staff Scientist will lead and support research projects focused on epitranscriptomic regulation of pancreatic islet biology and diabetes. The individual will design and execute experimental studies examining m6A-mediated gene regulation using biochemical, molecular, genomic, and computational approaches.
Responsibilities include developing and optimizing sequencing-based assays, conducting bioinformatic analyses of large genomic datasets, mentoring trainees, contributing to manuscript and grant preparation, and supporting collaborative projects involving human pancreatic islets.
The Staff Scientist will play a central role in developing and implementing advanced methodologies including J2 immunoprecipitation sequencing (J2-IP-seq), m6A profiling approaches, single-cell m6A sequencing, and integrative multi-omics analyses.
Compensation
FLSA Status
Exempt
Pay Range
$80,000.00 - $100,000.00 The included pay rate or range represents the University’s good faith estimate of the possible compensation offer for this role at the time of posting.
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