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Eisai
Pennsylvania, Exton; Exton
Source: Eisai careers · View original posting
From Eisai's posting. “We” and “our” refer to the employer.
At Eisai, satisfying unmet medical needs and increasing the benefits healthcare provides to patients, their families, and caregivers is Eisai’s human health care (hhc) mission. We’re a growing pharmaceutical company that is breaking through in neurology and oncology, with a strong emphasis on research and development. Our history includes the development of many innovative medicines, notably the discovery of the world's most widely-used treatment for Alzheimer’s disease.
As we continue to expand, we are seeking highly-motivated individuals who want to work in a fast-paced environment and make a difference. If this is your profile, we want to hear from you.
Job Summary
The Principal Researcher of Downstream Development will be responsible for executing laboratory scale experiments for all aspects of protein purification including chromatography, filtration and membrane separations (TFF, UFDF, microfiltration, viral filtration, and depth filtration), investigating and evaluating novel technologies to improve current purification processes, participating in internal/external technology transfers, performing standard analytical methods to characterize biologics and reagents including UV/Vis
spectroscopy, HPLC, electrophoresis and ELISA, participate in design, planning and execution of viral clearance studies and planning and execution of process validation experiments in support of late stage products. The individual will also be responsible for maintaining PD equipment and laboratories to ensure efficient, safe and effective operations of the laboratory. The individual might also participate in project sub teams and provide cross-functional support for other departments at the discretion of management.
Essential Functions
Under minimal supervision, design and performs laboratory Experiments for early and late-stage biologic drug products, support viral clearance studies, support authoring of regulatory documents, maintain critical data in laboratory notebooks, and maintain PD equipment and laboratories to ensure efficient and effective operations of the laboratory
Under minimal supervision perform scale up and tech transfer of purification processes for internal GMP production and to external partners and CMOs.
Writing, preparation and review of technical reports, presentations and protocols.
Perform characterization assays such as concentration measurements, HPLC SEC, capillary electrophoresis, and ELISA to support purification process development and reagent preparation activities.
Order supplies, manage samples, discard expired reagents and perform housekeeping and other laboratory maintenance tasks to assure laboratories are continuously maintained in a safe, orderly and efficient condition.
Interact cross-functionally with Upstream Process Development, Operations, Facilities, R&D, Quality Assurance, Quality Control, Validation, QC Biochemistry, and other internal and external functions to support successful product development.
The annual base salary range for the Principal Researcher, Downstream Process Development - Biologics is from :$80,200-$105,200
Under current guidelines, this position is eligible to participate in : Eisai Inc. Annual Incentive Plan.
Final pay determinations will depend on various factors including but not limited to experience level, education, knowledge, and skills.
Employees are eligible to participate in Company employee benefit programs. For additional information on Company employee benefits programs, visit https://careers.eisai.com/us/en/compensation-and-benefits .
Certain other benefits may be available for this position, please discuss any questions with your recruiter.
Eisai Inc. participates in E-Verify. E-Verify is an Internet based system operated by the Department of Homeland Security in partnership with the Social Security Administration that allows participating employers to electronically verify the employment eligibility of all new hires in the United States. Please click on the following link for more information:
Right To Work
E-Verify Participation
Eisai is an equal opportunity employer and as such, is committed in policy and in practice to recruit, hire, train, and promote in all job qualifications without regard to race, color, religion, gender, age, national origin, citizenship status, marital status, sexual orientation, gender identity, disability or veteran status. Similarly, considering the need for reasonable accommodations, Eisai prohibits discrimination against persons because of disability, including disabled veterans.
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