layiq

/la·yiq/adjective

worthy; deserving; fitting; suitable.

A role, opportunity, or path that merits attention, time, and pursuit.

Associate Scientist or Scientist- dos Santos's Lab at St. Jude | LAYIQ

Animal Studies
Design, coordinate, and execute studies using genetically engineered, syngeneic, transplantation, and treatment-based mouse models of mammary gland biology and breast cancer.
Manage mouse breeding strategies, cohort generation, genotyping plans, experimental randomization, and longitudinal monitoring.
Perform or oversee animals procedure and tissue collection
Develop and maintain detailed experimental timelines and animal-cohort records.
Assist with preparation, implementation, and amendment of IACUC protocols.
Ensure compliance with institutional animal-welfare policies, biosafety requirements, and approved experimental procedures.
Support the training of laboratory personnel in relevant animal procedures and confirm technical competency.
Organoid and Ex Vivo Models
Establish, maintain, and optimize primary mammary epithelial and tumor organoid cultures from mouse and human specimens.
Design and conduct organoid assays evaluating growth, differentiation, lineage plasticity, hormone response, extracellular-matrix interactions, and therapeutic sensitivity.
Develop co-culture systems incorporating fibroblasts, immune cells, extracellular-matrix components, or other microenvironmental populations.
Perform organoid-forming, branching, invasion, viability, differentiation, and drug-response assays.
Molecular, Cellular, and Tissue Analysis
Perform or supervise molecular and cellular assays, including flow cytometry, immunofluorescence, immunohistochemistry, microscopy, quantitative image analysis, western blotting, qPCR, ELISA, and related approaches.
Support thre preparation of high-quality specimens for bulk RNA sequencing, single-cell RNA sequencing, spatial profiling, epigenomic assays, proteomics, and other molecular analyses.
Maintain detailed, accurate, and reproducible experimental records.
Scientific and Project Leadership
Collaborate with the principal investigator to develop experimental strategies, establish project priorities, and evaluate feasibility.
Analyze and interpret data using appropriate statistical and computational methods.
Identify technical or conceptual problems and develop practical solutions.
Present findings at laboratory meetings, departmental seminars, and collaborative meetings.
Promote communication and coordination among laboratory members and external collaborators.
Minimum Education and/or Training: Bachelor's degree in relevant scientific areas such as cancer biology, cell biology, molecular biology, developmental biology, biomedical sciences, or a related discipline is required.
PhD, or equivalent doctoral degree strongly preferred.
Scientist Minimum Experience: Eight (8) years of relevant work experience is required
Six (6) years of relevant work experience is required with a Master's degree
Three (3) years of relevant work experience is required with a PhD

Associate Scientist or Scientist- dos Santos's Lab

Employer job description

What You Will Do

Associate Scientist Minimum Experience:

Compensation

Equal opportunity and accommodations

About this listing