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BioAgilytix
Durham, NC
Source: BioAgilytix careers · View original posting
From BioAgilytix's posting. “We” and “our” refer to the employer.
At BioAgilytix, we are passionate about premier science and the impact it has on our world. Our team of highly experienced scientists and professionals deliver tailored services for supporting new medicine breakthroughs with best-in-class bioanalytical services. We are tirelessly committed to our customers by being solution-oriented and deadline-driven. . . and we are growing. Our culture is fast-paced, fun and never boring. Because we work across numerous clients and drug modalities, your career can develop rapidly.
You’ll gain experience with a variety of challenges all while you enable life-changing, life-saving therapeutics to the patients who need them.
In this hands-on, laboratory-based Scientist role, you will design, develop, and execute bioanalytical methods and experiments supporting the advancement of new therapies, with a particular focus on large-molecule LC/MS applications. You’ll spend much of your time at the bench performing method development, optimization, and GxP-compliant validation; generating and analyzing data; evaluating assay performance; and conducting targeted and untargeted analyses using liquid chromatography and mass spectrometry.
This role is a strong fit for someone who enjoys being in the lab, working through complex scientific problems, and seeing a method through from development to validation and execution. You’ll work across a variety of client programs and therapeutic areas, which means the science and day-to-day challenges can vary quite a bit. We’re looking for someone with strong LC/MS experience who is comfortable working in a regulated environment and understands the importance of producing accurate, high-quality data.
Essential Responsibilities: Lead assay development, validation, and sample analysis of biologics, proteins, peptides, ADCs, and/or biomarkers using chromatographic and mass spectrometric (LC/MS) techniques in support of preclinical, clinical, and product release studies.
Plan and direct experimental design for junior staff
Drive bioanalytical projects to align with client timelines
Frequent communication with clients to discuss technical details and provide project updates.
Minimum Preferred Qualifications: Skills: Experience with development, validation and execution of chromatographic and mass spectrometric assays (LC/MS), and/or ability to perform most tasks associated with custom research planning and bench work
Ability to develop protein binding, CYP inhibition, CYP induction, or CYP phenotyping and/or ability to develop chromatographic assays using HPLC or LC/MS/MS.
Experience working in a GxP environment preferred
Excellent oral and written communication skills
Minimum Preferred Qualifications: Education/Experience: Bachelor’s degree in chemistry, biochemistry, biotechnology, biology, immunology, or related field with not less than 12 years’ experience in a scientific laboratory environment; or
Master’s degree in chemistry, biochemistry, biotechnology, biology, immunology, or related field with not less than ten (10) years’ experience in a scientific laboratory environment; or
PhD in chemistry, biochemistry, biotechnology, biology, immunology, or related field with not less than eight (8) years’ experience in a scientific laboratory environment
Demonstrated expertise in developing chromatographic and mass spectrometric assays including LC/MS and LC/MS/MS for bioanalytical studies by extracting analytes of interest from complex biological matrices using protein precipitation, liquid-liquid, solid phase, immunoprecipitation or other extraction technique
Ability to communicate information and ideas so others will understand, with the ability to listen to and understand information and ideas presented through spoken words and sentences
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