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Stanford University
Stanford, CA, United States
Source: Stanford University careers · View original posting
From Stanford University's posting. “We” and “our” refer to the employer.
Applying a comprehensive understanding for the theories and methods of a life science discipline, perform work directly involved in research projects, interpreting results and participation in experimental design.
The Mourrain Lab, within the Department of Psychiatry & Behavioral Sciences at Stanford University’s School of Medicine, is seeking a full time Life Science Research Professional 1 (LSRP 1) to study sleep and its effects on neurobiology. The Mourrain Lab specializes in neuroscience, genetics, epigenetics, developmental biology, and engineering to achieve the following objectives:
Investigate the reasons behind sleep and how it enhances cognitive performance by altering synaptic connections.
Identify and address synaptic deficits observed in neurodevelopmental conditions like Fragile X syndrome, Autism, neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and age-related synaptic changes.
Study genes and processes essential for neuronal regeneration to repair damaged brain tissue, including the retina.
Enhance knowledge of gene regulation mechanisms and explore the impact of non-coding Single Nucleotide Polymorphisms (SNPs) on causing human diseases.
The LSRP 1 will test the impact of sleep disruptions and sleep interventions on autophagosomal activity and cellular redox homeostasis mechanisms. The LSRP will perform CRISPR/Cas9 editing of genes involved in lysosomal and phagosome activity. They will perform molecular analysis of the generated mutations and biochemical phenotyping.
Bachelor’s degree in Molecular Biology, Biochemisty or related field or MSc desired
Prior experience performing biology/gene editing, biochemistry related to oxidative stress, and animal biology.
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