HEOR Science Liaison

Company introduction:

Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to unlocking urgently needed new treatment options in mental health care.

The Company is headquartered in London, UK, with a U.S. office in New Jersey. We believe mental health patients deserve the possibility of a better future. Our initial focus is developing COMP360 psilocybin, a proprietary, investigational, synthetic psilocybin treatment under evaluation for treatment-resistant depression (TRD) and post-traumatic stress disorder (PTSD). COMP360 is a potentially first-in-class treatment and has Breakthrough Therapy designation from the U.S.

Food and Drug Administration (FDA), as well as Innovative Licensing and Access Pathway (ILAP) designation in the UK for TRD.

We are leading the world’s largest classic psychedelic clinical program in TRD, and building upon that robust foundation, we are executing a late-stage trial evaluating COMP360 for PTSD, another condition with high unmet need. Our goal is to advance treatments that move the field of psychiatry towards treatment options that offer rapid onset and sustained durability with infrequent dosing. -

Compass Pathways

Job overview:

The Field-Based Health Economics & Outcomes Research (HEOR) Science Liaison is a scientifically trained, field-based expert, serving as a scientific bridge to external healthcare decision makers (HCDMs), including MCOs, PBMs, IDNs, ACOs, SPPs, and HTA bodies.

The HEOR Science Liaison delivers credible, non-promotional scientific exchange across clinical evidence, real-world evidence (RWE), pharmacoeconomics, and health outcomes to support informed formulary, coverage, and reimbursement decisions. The role spans the full product lifecycle and is key to demonstrating the value of innovative therapies to payer and access stakeholders.

Location:

Remote in the United States.

Reports to:

Director, HEOR.

Roles and responsibilities

(

Include but are not limited to ):

External Scientific Engagement

Identify, cultivate, and maintain peer-to-peer relationships with key payer thought leaders, formulary decision makers, Chief Medical Officers, Chief Pharmacy Officers, and other HCDMs within assigned geography

Deliver fair-balanced, scientifically rigorous presentations on clinical data, real-world evidence, pharmacoeconomic models, budget impact analyses, and patient-reported outcomes (PROs)

• Respond to unsolicited medical information requests from payer and access stakeholders with accurate, compliant, and timely scientific content
• Attend and represent the organization at managed care, payer, and scientific conferences to maintain awareness of current landscape issues and emerging data
• HEOR Evidence Generation & Dissemination

Partner with internal HEOR, RWE, and Medical Affairs teams to identify evidence gaps and support the design, execution, and dissemination of field-based observational studies, retrospective analyses, and pharmacoeconomic research

• Facilitate investigator-initiated and collaborator-initiated research proposals; coordinate with appropriate internal stakeholders for review and approval
• Support development and communication of health economic models, cost-effectiveness analyses, and budget impact tools for payer audiences
• Contribute to publications, posters, and abstracts for scientific meetings and peer-reviewed journals
• Payer Landscape Intelligence & Insights
• Gather and synthesize field intelligence on evolving payer policies, formulary decisions, coverage criteria, value-based contracting trends, and competitive landscape dynamics
• Communicate insights to internal stakeholders including Medical Affairs, Market Access, HEOR, and Commercial teams to inform strategy and evidence planning
• Monitor and interpret changes in managed care regulations, government payer policy (CMS, Medicare, Medicaid, VA/DoD), and HTA methodologies
• Cross-Functional Collaboration & Training

Serve as a scientific resource to Market Access Account Directors, Commercial teams, and other field-based colleagues; provide training on disease state, clinical data, and health economics topics

Collaborate with Medical Science Liaisons (MSLs), Global Medical Affairs, and HEOR headquarters teams to align field activities with overarching medical strategy

Appropriately collaborate with the Market Access team to educate and inform payers about clinical and health economic aspects of Compass Pathways’ investigational and on-market products

Participate in advisory board activities, scientific symposia, and payer-focused medical education programs

Complete all required training, compliance reporting, and administrative responsibilities in accordance with corporate policy and applicable law

Candidate Profile:

Advanced degree required, M.D., D.O., Pharm.D., or Ph.D. preferred, in a relevant scientific or health-related discipline (health economics, pharmacoeconomics, epidemiology, health services research, public health, or clinical sciences)

Minimum 2-3 years of experience in the capacity of field-based liaison, working with a pharmaceutical company, presenting to and engaging with payer customers, in collaboration with the Market Access function

• Minimum 3–5 years of experience in managed care, PBM, CMS/Medicare/Medicaid/VA/DoD, health care consulting, pharmaceutical industry, or a related access/HEOR environment
• Demonstrated knowledge of health economics methodology, including cost-effectiveness analysis, budget impact modeling, QALYs, systematic reviews, and meta-analyses
• Strong understanding of the US payer landscape, formulary management, and reimbursement processes
• Proven ability to translate complex scientific and economic data into clear, compelling narratives for payer and access audiences
• Valid driver’s license and ability to travel 50–70% of the time by car and air

Sponsorship:

Unfortunately, we cannot sponsor employment visas and can only accept applications if you have employment rights in the country to which you are applying.

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